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Cyproterone can cause side effects such as fatigue, low mood, and fulminant hepatitis. Orchiectomy allows individuals to stop taking these medications and avoid these adverse effects. [1] It is also an alternative for trans women who have contraindications to antiandrogens and is a minimally invasive procedure to eliminate testosterone levels. [11]
Therapy for those who refuse surgery, cannot have surgery, or do not have a pelvic mass may include hormonal therapy to suppress ovarian function. [3] Some women have symptoms consistent with endometriosis, including difficult or painful intercourse; urinary symptoms; or bowel symptoms. It is likely that some women with ORS don't have any ...
Symptoms can be very different from person to person, varying in range and intensity. About 25% of individuals have no symptoms, [1] [11] while for some it can be a debilitating disease. [12] Common symptoms include pelvic pain, heavy and painful periods, pain with bowel movements, painful urination, pain during sexual intercourse and infertility.
The signs and symptoms of NCS are all derived from the outflow obstruction of the left renal vein. The compression causes renal vein hypertension, leading to hematuria (which can lead to anemia) [4] and abdominal pain (classically left flank or pelvic pain). [5] The abdominal pain may improve or worsen depending on positioning. [5]
Most bilateral oophorectomies (63%) are performed without any medical indication, and most (87%) are performed together with a hysterectomy. [9] Conversely, unilateral oophorectomy is commonly performed for a medical indication (73%; cyst, endometriosis, benign tumor, inflammation, etc.) and less commonly in conjunction with hysterectomy (61%).
A related diagnosis is nutcracker syndrome where the left renal vein is described as being compressed between the aorta and the superior mesenteric artery. This is reported to cause collateral flow paths to open up to drain the left kidney i.e. reversed flow (reflux caudally) in the left renal vein.
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