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Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
A 2008 review found that the efficacy of single-dose treatments for hookworm infections were as follows: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [29] This substantiates prior claims that albendazole is much more effective than mebendazole for hookworm infections.
In humans, treatment is by anthelminthic medications, such as albendazole and mebendazole. [13] Treatment in animals can be done with a variety of anthelminthics. [1] A high-protein diet, supplemental iron, or a blood transfusion may also be necessary. [1] Levamisole and pyrantel pamoate are also used to treat hookworm anemia and hookworm disease.
In contrast, hookworms and whipworms can be eliminated at any time with a course of albendazole, made by GlaxoSmithKline . Strangely, a more pressing concern is keeping the creatures alive.
The efficacy of single-dose treatments for hookworm infections were: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [18] A current concern with this parasite is the increase in drug resistance, such as benzimidazoles and mebendazoles. [19] Pregnant women should not be treated within their first trimester. [9]
This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. [2] It is taken by mouth. [2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash. [2] A lower dose should be used in people with liver disease. [2]