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A coloboma (from the Greek κολόβωμα, meaning "defect") [1] is a hole in one of the structures of the eye, such as the iris, retina, choroid, or optic disc.The hole is present from birth and can be caused when a gap called the choroid fissure, which is present during early stages of prenatal development, fails to close up completely before a child is born.
Macular hole on the right eye Classification of Vitreomacular Adhesion, Traction, and Macular Hole (IVTS 2013) Macular degeneration is a condition affecting the tissues lying under the retina, while a macular hole involves damage from within the eye, at the junction between the vitreous and the retina itself. There is no relationship between ...
Retinoschisis is an eye disease characterized by the abnormal splitting of the retina's neurosensory layers, usually in the outer plexiform layer.Retinoschisis can be divided into degenerative forms which are very common and almost exclusively involve the peripheral retina and hereditary forms which are rare and involve the central retina and sometimes the peripheral retina.
Traction caused by VMA is the underlying pathology of an eye disease called symptomatic VMA. There is evidence that symptomatic VMA can contribute to the development of several well-known eye disorders, such as macular hole and macular pucker, that can cause visual impairment, including blindness.
Watzke-Allen test is a test used in the diagnosis of a macular hole. It is a subjective test based on photoreceptor displacement. [1] Test can be used to differentiate full thickness macular hole from other similar conditions and also to assess retinal function after surgical closure of the hole. [2] [3]
When the retina detaches, common symptoms include seeing floaters, flashing lights, a dark shadow in vision, and sudden blurry vision. [1] [3] The most common type of retinal detachment is rhegmatogenous, which occurs when a tear or hole in the retina lets fluid from the center of the eye get behind it, causing the retina to pull away. [6]
Leber congenital amaurosis (LCA) has been a major focus in the development of gene therapy for treatment of the disease, as it is the most severe form of congenital blindness and accounts for 5% of all inherited retinal diseases cases. [34] [35] Research on gene therapy is aimed at slowing retinal degeneration and improving visual function. [36]
Barrage laser is at times done prophylactically around a hole or tear associated with lattice degeneration in an eye at risk of developing a retinal detachment. It is not known if surgical interventions such as laser photocoagulation or cryotherapy are effective in preventing retinal detachment in patients with lattice degeneration or ...