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The subarachnoid lymphatic-like membrane (SLYM) is a possible fourth meningeal layer that was proposed in 2023 in the brain of humans and mice. [10] The SLYM is located in the subarachnoid space, the space between the middle reticular meninges and the innermost tender meninges that lie close to the brain. [10]
The dura mater covering the spinal cord is known as the dural sac or thecal sac, and only has one layer (the meningeal layer) unlike cranial dura mater. The potential space between these two layers is known as the epidural space, [5] which can accumulate blood in the case of traumatic laceration to the meningeal arteries.
The spinal cord (and brain) are protected by three layers of tissue or membranes called meninges, that surround the canal. The dura mater is the outermost layer, and it forms a tough protective coating.
Pia mater (/ ˈ p aɪ. ə ˈ m eɪ t ər / or / ˈ p iː ə ˈ m ɑː t ər /), [1] often referred to as simply the pia, is the delicate innermost layer of the meninges, the membranes surrounding the brain and spinal cord.
The arachnoid mater is interposed between the two other meninges, the more superficial (closer to the surface) and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The delicate arachnoid layer is not attached to the inside of the dura but against it, and surrounds the brain and spinal cord.
Embryologically, the arachnoid trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges. The initial development of the subarachnoid space occurs in two phases: [13] A mesenchymal layer "invades" between the embryonic epithelium and the developing neuroepithelium of the telencephalon.
Leptomeningeal collaterals lie within the leptomeninges, the two deep layers of the meninges called the pia mater and the arachnoid mater. [4] Their diameter has been measured at approximately 300 micrometers, [ 5 ] but there is variability between individuals in the size, quantity and location of these vessels, and between either hemisphere ...
In the skull, the periosteal layer of the dura mater adheres to the inner surface of the skull bones while the meningeal layer lays over the arachnoid mater. Between them is the epidural space . The two layers of the dura mater separate at several places, with the meningeal layer projecting deeper into the brain parenchyma forming fibrous septa ...