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Spermatocytic tumor is a rare tumour, making up only one to two percent of all testicular germ cell tumours. Men presenting with this tumour are generally 50 to 60 years old, and its occurrence is rare in men under 30 years old. Most present with slow, painless testicular enlargement, which may involve both testes. [1]
ICD-O Peak Age (yr) Benign or malignant Histology Tumor marker Germinoma (including dysgerminoma and seminoma) 40–50 Malignant Sheets of uniform polygonal cells with cleared cytoplasm; lymphocytes in the stroma About 10% have elevated hCG: Dysgerminoma: M9060/3: Seminoma: M9061/3: Placental alkaline phosphate (PLAP) [8]
A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages. [3] Testicular seminoma originates in the germinal epithelium of the seminiferous ...
The World Health Organization classification of testicular tumours [4] subdivides ITGCN into (1) a more common, unspecified type (ITGCNU), and (2) other specific subtypes. The most common specific subtypes are intratubular embryonal carcinoma and intratubular seminoma. [citation needed]
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
Globally testicular cancer resulted in 8,300 deaths in 2013 up from 7,000 deaths in 1990. [9] Testicular cancer has the highest prevalence in the U.S. and Europe, and is uncommon in Asia and Africa. [67] Worldwide incidence has doubled since the 1960s, [68] with the highest rates of prevalence in Scandinavia, Germany, and New Zealand. [citation ...
It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation needed] A 7.4 x 5.5-cm seminoma in a radical orchiectomy specimen from a 27-year-old man . Seminoma is the second-most common testicular cancer; the most common is mixed, which may contain seminoma. [citation needed]
In the testis pure embryonal carcinoma is also uncommon, and accounts for approximately ten percent of testicular germ cell tumours. However, it is present as a component of almost ninety percent of mixed nonseminomatous germ cell tumours. The average age at diagnosis is 31 years, and typically presents as a testicular lump which may be painful.