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Thyrotropin-releasing hormone has a stimulatory effect on prolactin release, although prolactin is the only anterior pituitary hormone whose principal control is inhibitory. Several variants and forms are known per species. Many fish have variants prolactin A and prolactin B. Most vertebrates, including humans, also have the closely related ...
Prolactin-releasing peptide (PrRP) is a peptide hormone that in humans is encoded by the PRLH gene. [5] PrRP stimulates prolactin (PRL) release and regulates the expression of prolactin through binding to the prolactin-releasing peptide receptor (GPR10).
A prolactin cell (also known as a lactotropic cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell in the anterior pituitary which produces prolactin (a peptide hormone) in response to hormonal signals including dopamine (which is inhibitory), thyrotropin-releasing hormone and estrogen (especially during pregnancy), which are stimulatory.
Prolactin (or leuteotropic hormone) PRL Peptide: anterior pituitary, uterus: lactotrophs of anterior pituitary Decidual cells of uterus: PRL receptor: milk production in mammary glands sexual gratification after sexual acts: 54 Prolactin-releasing hormone: PRLH Peptide: hypothalamus: Release prolactin from anterior pituitary: 55 Relaxin: RLN ...
Prolactin-releasing hormone, also known as PRLH, is a hypothetical human hormone or hormone releasing factor.Existence of this factor has been hypothesized as prolactin is the only currently known hormone for which almost exclusively negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor.
Unlike most tropic hormones released by the anterior pituitary gland, prolactin secretion is primarily regulated by hypothalamic inhibition rather than by negative feedback from peripheral hormones. Prolactin also self-regulates through a counter-current flow in the hypophyseal pituitary portal system, which triggers the release of hypothalamic ...
VIP in the pituitary helps to regulate prolactin secretion; it stimulates prolactin release in the domestic turkey. [19] Additionally, the growth-hormone-releasing hormone (GH-RH) is a member of the VIP family and stimulates growth hormone secretion in the anterior pituitary gland. [20] [21]
The hormone oxytocin, similarly to prolactin, has been found to increase with an increase in estrogen and the presence of infant cues such as suckling. [ 19 ] Oxytocin has been found in other non-human species to inhibit the rejection of offspring; [ 4 ] oxytocin is essential for responsive and sensitive caregiving.