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Empty sella syndrome is the condition when the pituitary gland shrinks or becomes flattened, filling the sella turcica with cerebrospinal fluid instead of the normal pituitary. [2] It can be discovered as part of the diagnostic workup of pituitary disorders, or as an incidental finding when imaging the brain.
The empty sella sign occurs due to herniation of the subarachnoid space into the sella turcica, displacing the pituitary gland and allowing CSF to occupy the space. [3] This phenomenon is often linked to the following mechanisms: [4] Primary empty sella syndrome occurs without an underlying cause or pituitary pathology. It is associated with a ...
Empty sella syndrome is the condition of a shrunken or flattened pituitary gland.. Since the sella turcica forms a bony caudal border for the pituitary gland, a pituitary tumor usually extends upward in the rostral direction into the suprasellar region.
The pituitary may also be affected by infections of the brain (brain abscess, meningitis, encephalitis) or of the gland itself, or it may be infiltrated by abnormal cells (neurosarcoidosis, histiocytosis) or excessive iron (hemochromatosis). Empty sella syndrome is unexplained disappearance of pituitary tissue, probably due to outside pressure.
Empty sella syndrome, ... [29] A rare form of dementia known as brain sagging dementia may be caused by a sagging brain, a characteristic of intracranial hypotension.
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The exact prevalence of this syndrome is difficult to define because the incidence varies so much from country to country. Sheehan syndrome is more prevalent in developing countries than developed countries. [15] In a study from the United Kingdom in 2001 only 1.4% of patients with hypopituitarism were diagnosed with Sheehan's syndrome. [6]
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