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In bacteria, the coding regions typically take up 88% of the genome. [1] The remaining 12% does not encode proteins, but much of it still has biological function through genes where the RNA transcript is functional (non-coding genes) and regulatory sequences, which means that almost all of the bacterial genome has a function. [1]
Long non-coding RNA/lncRNA: Non-coding RNA transcripts that are more than 200 nucleotides long. Members of this group comprise the largest fraction of the non-coding transcriptome other than introns. It is not known how many of these transcripts are functional and how many are junk RNA. transfer RNA/tRNA; micro RNA/miRNA: 19-24 nucleotides (nt ...
Noncoding sequences (ncDNA) are those that do not code for proteins. They include elements such as pseudogenes, segmental duplications, binding sites and RNA genes. [28] Pseudogenes are mutated copies of protein-coding genes that lost their coding function due to a disruption in their open reading frame (ORF), making them untranslatable. [28]
It is not known whether such hypovariable control regions are more widespread. In the Ayu (Plecoglossus altivelis), an East Asian protacanthopterygian, control region mutation rate is not markedly lowered, but sequence differences between subspecies are far lower in the control region than elsewhere. This phenomenon completely defies ...
Further, in order to generate a cyclic Hadamard core, the vector (of coefficients of) () when operated upon with the cyclic shift operation must be of period , and the vector difference of two arbitrary rows of (augmented with zero) must satisfy the uniformity condition of Butson, [5] previously referred to as Property U.
The mtDNA control region is an area of the mitochondrial genome which is non-coding DNA. This region controls RNA and DNA synthesis. [1] It is the most polymorphic region of the human mtDNA genome, [2] with polymorphism concentrated in hypervariable regions. The average nucleotide diversity in these regions is 1.7%. [3]
Phylogenetic footprinting is a technique used to identify transcription factor binding sites (TFBS) within a non-coding region of DNA of interest by comparing it to the orthologous sequence in different species. When this technique is used with a large number of closely related species, this is called phylogenetic shadowing. [1]
Moreover, non-coding RNAs like SINEs can bind or interact directly with the DNA duplex coding the gene and thus prevent its transcription. [15] Also, many non-coding RNAs are distributed near protein-coding genes, often in the reverse direction. This is especially true for short-interspersed nuclear elements as seen in Usmanova et al.