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Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC). [2] [3] [4] It belongs to the tyrosine kinase inhibitor family of medications. [5]
ERBB is abbreviated from erythroblastic oncogene B, a gene originally isolated from the avian genome. The human protein is also frequently referred to as HER2 (human epidermal growth factor receptor 2) or CD340 (cluster of differentiation 340). [5] [6] [7] HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 14 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Life expectancy may be plateauing. Don’t expect your grandkids to live to 200 years old. A study published on Monday suggests we may be reaching our limit in terms of life expectancy and that ...
In the United States, it is indicated for the treatment of adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with an aromatase inhibitor as initial endocrine-based therapy; or fulvestrant as initial endocrine-based therapy or following disease progression on endocrine therapy in ...
IHME noted that life expectancy gains nationwide are not keeping pace with other countries. The US’ global ranking is expected to decline to 66th in 2050 among 204 countries and territories.
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