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Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
B12 is crucial for many important functions, and, with a few exceptions, the only way to get it is through animal-based foods or B12 supplements. “Vitamin B12 is an essential water-soluble ...
Streptomyces griseus, a bacterium once thought to be a fungus, was the commercial source of vitamin B 12 for many years. [133] The species Pseudomonas denitrificans and Propionibacterium freudenreichii subsp. shermanii are more commonly used today. [ 132 ]
Vitamin B12 does also accumulate in a few plant-based sources, including some mushrooms, seaweed, and nutritional yeast, but not enough to fortify vegans, who, in particular, should consider being ...
In a trial on adult volunteers, this dose did not lead to a significant increase in serum vitamin B 12 levels when given thrice daily for one week. In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse ...
Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [150] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]