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  2. Methylcobalamin - Wikipedia

    en.wikipedia.org/wiki/Methylcobalamin

    Methylcobalamin (mecobalamin, MeCbl, or MeB 12) is a cobalamin, a form of vitamin B 12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. [1] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. [2]

  3. Vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12

    "B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...

  4. Vitamin B12-binding domain - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12-binding_domain

    In molecular biology, the vitamin B12-binding domain is a protein domain which binds to cobalamin (vitamin B12). It can bind two different forms of the cobalamin cofactor, with cobalt bonded either to a methyl group (methylcobalamin) or to 5'-deoxyadenosine (adenosylcobalamin).

  5. Methylmalonyl-CoA - Wikipedia

    en.wikipedia.org/wiki/Methylmalonyl-CoA

    Vitamin B 12 plays an integral role in this reaction. Coenzyme B 12 (adenosyl-cobalamin) is an organometallic form of Vitamin B 12 and serves as the cofactor of Methylmalonyl-CoA mutase, which is an essential enzyme in the human body. [4] The transformation of Methylmalonyl-CoA to Succinyl-CoA by this enzyme is a radical reaction. [4]

  6. Vitamin B12 deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12_deficiency

    Vitamin B 12 deficiency is preventable with supplements, which are recommended for pregnant vegetarians and vegans, and not harmful in others. [2] Risk of toxicity due to vitamin B 12 is low. [2] Vitamin B 12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the ...

  7. Cobalamin biosynthesis - Wikipedia

    en.wikipedia.org/wiki/Cobalamin_biosynthesis

    Cobalamin biosynthesis is the process by which bacteria and archea make cobalamin, vitamin B 12. Many steps are involved in converting aminolevulinic acid via uroporphyrinogen III and adenosylcobyric acid to the final forms in which it is used by enzymes in both the producing organisms and other species, including humans who acquire it through ...

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