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Multiple forms of extrachromosomal DNA exist, and, while some of these serve important biological functions, [1] they can also play a role in diseases such as cancer. [2] [3] [4] In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids, whereas, in eukaryotes extrachromosomal DNA is primarily found in organelles. [1]
Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA structure that was first discovered in 1964 by Alix Bassel and Yasuo Hotta. [1] In contrast to previously identified circular DNA structures (e.g., bacterial plasmids, mitochondrial DNA, circular bacterial chromosomes, or chloroplast DNA), eccDNA are circular DNA found in the eukaryotic nuclei of plant and animal ...
In Mendelian inheritance, genes have only two alleles, such as a and A. Mendel consciously chose pairs of genetic traits, represented by two alleles for his inheritance experiments. In nature, such genes often exist in several different forms and are therefore said to have multiple alleles. An individual usually has only two copies of each gene ...
K80, the Kimura 1980 model, [3] often referred to as Kimura's two parameter model (or the K2P model), distinguishes between transitions (, i.e. from purine to purine, or , i.e. from pyrimidine to pyrimidine) and transversions (from purine to pyrimidine or vice versa). In Kimura's original description of the model the α and β were used to ...
K-Line Electric Trains is a brand name of O gauge and S gauge model railway locomotives, rolling stock, and buildings. Formerly the brand name under which Chapel Hill, North Carolina–based MDK Inc. sold its products, K-Line was then acquired by Sanda Kan, a Chinese toy manufacturer that formerly acted as K-Line's subcontractor.
Rivarossi model of 2-6-6-6. Rivarossi was founded in 1945 by Antonio Riva and Alessandro Rossi. [1] In the 1990s Rivarossi acquired Lima (1992), Jouef and Arnold (1997). In 2003 Rivarossi went into receivership. In 2004 Hornby Railways plc acquired assets from Rivarossi, in particular the brands Arnold, Jouef, Rivarossi and Lima. Since 2006 ...