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  2. Labrador Retriever coat colour genetics - Wikipedia

    en.wikipedia.org/wiki/Labrador_Retriever_coat...

    The interplay between these two genes determines the colour of a Labrador Retriever, and is widely used as an example of epistasis. If a dog possesses the dominant phenotype for the extension allele (genotype EE or Ee), then it will display the fur colouration determined by its brown locus genotype, while a dog with the recessive extension ...

  3. Gene therapy for color blindness - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_for_color...

    Gene therapy was to restore some of the sight of mice with achromatopsia. The results were positive for 80% of the mice treated. [7] In 2010, gene therapy for a form of achromatopsia was performed in dogs. Cone function and day vision have been restored for at least 33 months in two young dogs with achromatopsia.

  4. Dilution gene - Wikipedia

    en.wikipedia.org/wiki/Dilution_gene

    The dilute gene d is recessive to the wild type allele D. A gene test can be used to determine a dog's genotype concerning genes for pigmentation. In some dog breeds lightened by the dilute gene, the mutation d is associated with color dilution alopecia (CDA). Since not all breeds in which the gene occurs exhibit these problems, it is suspected ...

  5. Synthetic lethality - Wikipedia

    en.wikipedia.org/wiki/Synthetic_lethality

    Synthetic lethality is defined as a type of genetic interaction where the combination of two genetic events results in cell death or death of an organism. [1] Although the foregoing explanation is wider than this, it is common when referring to synthetic lethality to mean the situation arising by virtue of a combination of deficiencies of two or more genes leading to cell death (whether by ...

  6. This startup wants to use gene-editing to extend the ... - AOL

    www.aol.com/news/this-startup-wants-to-use-gene...

    Forever Friends, a spin-out company from Oxford University, hopes to dramatically expand the lifespan of dogs using new gene-editing technology. This startup wants to use gene-editing to extend ...

  7. Stargardt disease - Wikipedia

    en.wikipedia.org/wiki/Stargardt_disease

    Gene therapy is designed to insert a copy of a corrected gene into retinal cells. The hope is to return cell function back to normal and the treatment has the potential to stop disease progression. This therapy will not restore impaired vision back to normal. The research is being undertaken by a partnership between Sanofi and Oxford BioMedica.

  8. Heart failure is reversed with new gene therapy in animal ...

    www.aol.com/heart-failure-reversed-gene-therapy...

    Heart failure has historically been irreversible, but a new study suggests that could change. At the University of Utah, scientists used a new gene therapy that reversed heart failure in animals.

  9. Canine degenerative myelopathy - Wikipedia

    en.wikipedia.org/wiki/Canine_degenerative_myelopathy

    A dog with degenerative myelopathy often stands with its legs close together and may not correct an unusual foot position due to a lack of conscious proprioception. Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis (ALS).