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Esoterica is an over-the-counter topical ointment applied to the skin for the purpose of lightening freckles, age spots, chloasma, melasma, and other skin discolorations due to a benign localized increase in the production of melanin. Esoterica may have other appropriate medical uses as determined by a physician.
Hydroquinone is used as a topical application in skin whitening to reduce the color of skin. It does not have the same predisposition to cause dermatitis as metol does. This is a prescription-only ingredient in some countries, including the member states of the European Union under Directives 76/768/EEC:1976.
“Typically, over-the-counter concentrations of kojic acid are 1 to 2%,” says Castilla. “People with sensitive skin should keep in mind, higher concentrations are likely to be more irritating.”
Clobetasol propionate is a corticosteroid that is used to treat skin conditions such as eczema, contact dermatitis, seborrheic dermatitis, steroid responsive dermatosis, and psoriasis (including scalp and plaque-type). [8] [9] It is applied to the skin as a cream, foam, gel, liquid, solution, ointment, or shampoo.
[18] [19] Hydroquinone was the most commonly prescribed hyperpigmentation treatment before the long-term safety concerns were raised, [20] and the use of it became more regulated in several countries and discouraged in general by WHO. [21] For the US, only 2% is at present sold over-the-counter, and 4% needs prescription.
A container with cream. Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons, waxes, or polyethylene glycols as the vehicle for external skin application. [1]
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