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  2. Chromatin - Wikipedia

    en.wikipedia.org/wiki/Chromatin

    The arrangement of chromatin within the nucleus may also play a role in nuclear stress and restoring nuclear membrane deformation by mechanical stress. When chromatin is condensed, the nucleus becomes more rigid. When chromatin is decondensed, the nucleus becomes more elastic with less force exerted on the inner nuclear membrane. This ...

  3. Chromatid - Wikipedia

    en.wikipedia.org/wiki/Chromatid

    Chromatid pairs are normally genetically identical, and said to be homozygous. However, if mutations occur, they will present slight differences, in which case they are heterozygous . The pairing of chromatids should not be confused with the ploidy of an organism, which is the number of homologous versions of a chromosome.

  4. Chromosome regions - Wikipedia

    en.wikipedia.org/wiki/Chromosome_regions

    (1) Chromatid – one of the two identical parts of the chromosome after S phase. (2) Centromere – the point where the two chromatids touch, and where the microtubules attach. (3) Short arm (p). (4) Long arm (q). Several chromosome regions have been defined by convenience and convention in order to talk about gene loci.

  5. Chromosome - Wikipedia

    en.wikipedia.org/wiki/Chromosome

    This is an accepted version of this page This is the latest accepted revision, reviewed on 8 February 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...

  6. Nuclear organization - Wikipedia

    en.wikipedia.org/wiki/Nuclear_Organization

    The organization of chromosomes into distinct regions within the nucleus was first proposed in 1885 by Carl Rabl.Later in 1909, with the help of the microscopy technology at the time, Theodor Boveri coined the termed chromosome territories after observing that chromosomes occupy individually distinct nuclear regions. [6]

  7. Sister chromatids - Wikipedia

    en.wikipedia.org/wiki/Sister_chromatids

    Sister chromatid cohesion is essential for the correct distribution of genetic information between daughter cells and the repair of damaged chromosomes. Defects in this process may lead to aneuploidy and cancer, especially when checkpoints fail to detect DNA damage or when incorrectly attached mitotic spindles do not function properly.

  8. Eukaryotic chromosome structure - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_chromosome...

    Packaging of nucleosomes into higher order chromatin structures involves the use of loops and coils. In eukaryotes, such as humans, roughly 3.2 billion nucleotides are spread out over 23 different chromosomes (males have both an X chromosome and a Y chromosome instead of a pair of X chromosomes as seen in females). Each chromosome consists ...

  9. Nucleosome - Wikipedia

    en.wikipedia.org/wiki/Nucleosome

    Histone tails and their function in chromatin formation Since they were discovered in the mid-1960s, histone modifications have been predicted to affect transcription. [ 45 ] The fact that most of the early post-translational modifications found were concentrated within the tail extensions that protrude from the nucleosome core lead to two main ...