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The details of PCCI's causes and boundaries are not well known. [7] Two major theories have been advanced: [4] the direct effect of chemotherapy drugs on the brain, and the role of hormones in nervous system health. PCCI is complex and factors other than the chemotherapeutic agents may impact cognitive functioning.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Dermatologists explain how chemicals, manicures, nutrient deficiencies and even some medications or chronic conditions can cause peeling nails. Dermatologists explain how chemicals, manicures ...
2. You buffed your nails too much. Just as moisture-laden nails can be prone to peeling and splitting, so can nails that are dried out from too much buffing, according to Dr. Peters.
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
My hair, pre-Worst News Ever. I showed up at his New York City salon after work on a chilly night in November and walked up the stairs to the second floor.
The blood–brain barrier poses an obstacle to delivery of chemotherapy to the brain. This is because the brain has an extensive system in place to protect it from harmful chemicals. Drug transporters can pump out drugs from the brain and brain's blood vessel cells into the cerebrospinal fluid and blood circulation. These transporters pump out ...
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