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Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule. Typically, benzodiazepine withdrawal is characterized by ...
Benzodiazepines can be addictive and induce dependence even at low doses, with 23% becoming addicted within 3 months of use. Benzodiazepine addiction is considered a public health problem. Approximately 68.5% of prescriptions of benzodiazepines originate from local health centers, with psychiatry and general hospitals accounting for 10% each.
Protracted benzodiazepine withdrawal has been observed to occur in some individuals prescribed benzodiazepines. [8] [9] Drug use, including alcohol and prescription drugs, can induce symptomatology which resembles mental illness. This can occur both in the intoxicated state and during the withdrawal state.
A provider can help you figure out next steps, and if you’re concerned, they can adjust your dose, switch you to another med, or help you taper off your current one if needed.
Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug. [ 1 ] [ 2 ] Prescribed psychotropic drugs that may require tapering due to this physical dependence include opioids , [ 3 ] [ 4 ] [ 5 ] selective serotonin reuptake inhibitors , [ 6 ] antipsychotics , [ 7 ...
The most commonly used agents are long-acting benzodiazepines, such as chlordiazepoxide and diazepam. These are believed to be superior to other benzodiazepines for treatment of delirium and allow for longer periods between doses. However, benzodiazepines with intermediate half-lives like lorazepam may be safer in people with liver problems. [34]
Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders , insomnia , and seizures .
It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. [6] Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval, but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use. [7]