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The term "interstitial cystitis" was coined by Dr. Alexander Skene in 1887 to describe the disease. [13] In 2002, the United States amended the Social Security Act to include interstitial cystitis as a disability. The first guideline for diagnosis and treatment of interstitial cystitis is released by a Japanese research team in 2009. [71]
In interstitial cystitis, pentosan polysulfate is believed to work by providing a protective coating to the damaged bladder wall. Pentosan polysulfate is similar in structure to the natural glycosaminoglycan coating of the inner lining of the bladder , and may replace or repair the lining, reducing its permeability .
In addition to hydrodistension related glomerulations, a study by Rosamilia et al. has shown that biopsied bladders from women with interstitial cystitis have decreased vessel density in the subepithelium. With this, data collected by Irwin et al. also showed that blood perfusion in interstitial cystitis bladders is reduced.
[7] [18] In women, they are the most common form of bacterial infection. [19] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime. [4] [7] They occur most frequently between the ages of 16 and 35 years. [7] Recurrences are common. [7]
In 2007, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) began using the umbrella term urologic chronic pelvic pain syndromes , for research purposes, to refer to pain syndromes associated with the bladder (i.e. interstitial cystitis/painful bladder syndrome, IC/PBS) and the prostate gland (i.e. chronic prostatitis ...
We found the best technology for adults over 65 at CES this year. From AI aids to ‘aging in place’ smart home solutions, the annual tech show kept older users in mind.