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This results in the risk of gallbladder rupture which is life-threatening thus early diagnosis is necessary. [8] Additionally the composition of biliary sludge has been suggested to encourage the formation of a mucocele. Biliary sludge occurs when more water or mucin is reabsorbed and there is excessive bile salts.
Biliary sludge has been associated with pregnancy, rapid weight loss, total parenteral nutrition, drugs such as ceftriaxone and octreotide, solid organ transplantation, and gastric surgery. [1] [2] In many of these conditions, it is thought that the impairment in the contractility of the gallbladder leads to the formation of the sludge. [2]
[2] [3] Ceftriaxone has been frequently associated with biliary sludge or biliary pseudolithiasis in subsequent reports. [3] Ceftriaxone is excreted primarily through the urine , but also through the bile, up to 40% of its excretion, with concentrations in the bile 20-150 times higher than in the serum.
It shows a gallbladder wall that is almost pathologically thickened, at 3 mm. However, there is no apparent edema in the pericholecystic fat. The gallbladder contains biliary sludge, as well as gallstones, which create acoustic shadowing. There is thus gallstones without current cholecystitis.
Most polyps are benign and do not need to be removed. Surgical removal of the gallbladder (cholecystectomy) is recommended when a gallbladder polyp larger than 1 cm is found, even if the person has no symptoms clearly related to the polyp. Laparoscopic surgery is an option for small or solitary polyps. [citation needed]
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]
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Faith (December 22, 2002 - September 22, 2014) was a bipedal dog, born with three legs; two fully developed hind legs and a deformed front leg, which was amputated when she was seven months old after it began to atrophy. [1]