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Untreated gonorrhea can lead to major complications, such as: Infertility in women. Gonorrhea can spread into the uterus and fallopian tubes, causing pelvic inflammatory disease (PID). PID can result in scarring of the tubes, greater risk of pregnancy complications and infertility, and can be fatal, particularly in the immunocompromised.
If symptoms persist, follow-up with a urologist may be necessary to identify the cause. According to a study, tinidazole used with doxycycline or azithromycin may cure NGU better than when doxycycline or azithromycin is used alone. [8] If left untreated, complications include epididymitis and infertility.
[8] [10] Untreated infection may spread to the rest of the body (disseminated gonorrhea infection), especially the joints (septic arthritis). Untreated infection in women may cause pelvic inflammatory disease and possible infertility due to the resulting scarring. [11]
Untreated chlamydia and gonorrhea in women can lead to pelvic inflammatory disease which may lead to chronic pelvic pain, according to the World Health Organization.
Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen. In recent years, the prevalence of syphilis has declined in Western Europe, but it has increased in Eastern Europe (former Soviet states).
“Anybody who’s had a bladder infection, a real one, they know it’s miserable and symptoms are horrible, but they don’t look at it as something that could be potentially life-threatening ...
That’s concerning given that almost half of U.S. gonorrhea infections in 2022 were resistant to at least one antibiotic, according to a May 2024 report on super-gonorrhea published in JAMA ...
Symptoms that may occur include: a painful or burning sensation when urinating, an unusual discharge from the penis, testicular pain or swelling, or fever. If left untreated, chlamydia in men can spread to the testicles causing epididymitis, which in rare cases can lead to sterility if not treated. [15]