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Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. [1] The major function of this system is as a barrier against the external environment. [2]
The skin will appear paler than the surrounding skin surface once an injury has healed. [4] Different areas of the skin may be hypopigmented as a result of other genetic illnesses. Hypopigmentation can be caused by hereditary conditions such as vitiligo, melasma, pityriasis versicolor, pityriasis alba, albinism, and fungal infections. [4]
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Vitiligo occurs in three different patterns. Segmental depigmentation means only one side of the body is affected, whereas generalized depigmentation means many parts of the body are affected. [34] Jackson's autopsy report states a "focal depigmentation of the skin" [35] (i.e., the depigmentation occurs on one or a few areas of the body). [34]
Michael’s first child, Michael Joseph Jackson Jr., was born to the musician and nurse Debbie Rowe, […] “He had a lot of insecurity around, kind of looking blotchy in his appearance,” said ...
Vitiligo is a skin disease where people lack melanin in certain areas in the skin. People with oculocutaneous albinism typically have a very low level of melanin production. Albinism is often but not always related to the TYR gene coding the tyrosinase enzyme. Tyrosinase is required for melanocytes to produce melanin from the amino acid ...
Acne symptoms and signs. Acne blemishes are most common on the face, chest, back, shoulders and neck, but they can appear almost anywhere. With acne, you might have pimples, blackheads, papules ...