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Simethicone tablets. Simeticone is used to relieve the symptoms of excessive gas in the gastrointestinal tract, namely bloating, burping, and flatulence. [2] [3] While there is a lack of conclusive evidence that simeticone is effective for this use, [4] [5] [failed verification] studies have shown that it can relieve symptoms of functional dyspepsia [6] and functional bloating.
Consumer products to control flatulence often contain silicone oil. [citation needed] Silicone oils have been used as a vitreous fluid substitute to treat difficult cases of retinal detachment, such as those complicated with proliferative vitreoretinopathy, large retinal tears, and penetrating ocular trauma. [4] Additionally, silicone oil is ...
The rubbery, vinegary-smelling silicone caulks, adhesives, and aquarium sealants are also well-known. PDMS is also used as a component in silicone grease and other silicone based lubricants, as well as in defoaming agents, mold release agents, damping fluids, heat transfer fluids, polishes, cosmetics, hair conditioners and other applications.
The antacid, Maalox Maalox was a brand of antacid owned by Sanofi.Their main product is a flavored liquid containing a suspension of aluminum hydroxide and magnesium hydroxide, which act to neutralize or reduce stomach acid, for the purpose of relieving the symptoms of indigestion, heartburn, gastroesophageal reflux disease, and also stomach or duodenal ulcers.
Silicone grease is widely used as a temporary sealant and a lubricant for interconnecting ground glass joints, as is typically used in laboratory glassware.Although silicones are normally assumed to be chemically inert, several historically significant compounds have resulted from unintended reactions with silicones.
A combination of alverine citrate and simeticone (ACS) for irritable bowel syndrome therapy were compared with placebo in a phase IV clinical trial. [8] At week 4, the alverine citrate and simeticone group had lower VAS scores for abdominal pain/discomfort (median: 40 mm vs. 50 mm, P = 0.047) and higher responder rate (46.8% vs. 34.3%, OR = 1.3; P = 0.01) as compared with the placebo group.
Loperamide/simethicone is combination medication sold under the brand name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. It contains loperamide and simethicone.
These might be delivered as an oil or a water-based emulsion. The silicone compound consists of a hydrophobic silica dispersed in a silicone oil. Emulsifiers are added to ensure that the silicone spreads fast and well in the foaming medium. The silicone compound might also contain silicone glycols and other modified silicone fluids. [5]