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  2. C-peptide - Wikipedia

    en.wikipedia.org/wiki/C-peptide

    The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In the context of diabetes or hypoglycemia, a measurement of C-peptide blood serum levels can be used to distinguish between different conditions with similar clinical features.

  3. C-terminal telopeptide - Wikipedia

    en.wikipedia.org/wiki/C-terminal_telopeptide

    The CTX test measures for the presence and concentration of a crosslink peptide sequence of type I collagen, found, among other tissues, in bone. This specific peptide sequence relates to bone turnover because it is the portion that is cleaved by osteoclasts during bone resorption, and its serum levels are therefore proportional to osteoclastic ...

  4. Homeostatic model assessment - Wikipedia

    en.wikipedia.org/wiki/Homeostatic_model_assessment

    In this updated version it is possible to determine insulin sensitivity and β-cell function from paired fasting plasma glucose and radioimmunoassay insulin, specific insulin, or C-peptide concentrations. The authors recommend the computer software be used wherever possible. [4] [5]

  5. Insulin tolerance test - Wikipedia

    en.wikipedia.org/wiki/Insulin_tolerance_test

    An insulin tolerance test (ITT) is a medical diagnostic procedure during which insulin is injected into a patient's vein, after which blood glucose is measured at regular intervals. This procedure is performed to assess pituitary function, adrenal function, insulin sensitivity , [ 1 ] [ 2 ] and sometimes for other purposes.

  6. Copeptin - Wikipedia

    en.wikipedia.org/wiki/Copeptin

    Copeptin (also known as CT-proAVP) is a 39-amino acid-long peptide derived from the C-terminus of pre-pro-hormone of arginine vasopressin, neurophysin II and copeptin. . Arginine vasopressin (AVP), also known as the antidiuretic hormone (ADH), is encoded by the AVP gene and is involved in multiple cardiovascular and renal pathways and abnormal level of AVP are associated with various

  7. Mutated citrullinated vimentin - Wikipedia

    en.wikipedia.org/wiki/Mutated_citrullinated_Vimentin

    Anti-MCV antibodies are a member of the ACPA family, a group of the so-called antibodies to citrullinated protein/peptide antigens. Rheumatoid arthritis is an autoimmune disorder . Detection of specific autoantibodies (antibodies directed against the body’s own tissue) such as rheumatoid factors and ACPAs may provide indication of the disease.

  8. Anti–citrullinated protein antibody - Wikipedia

    en.wikipedia.org/wiki/Anti–citrullinated...

    However, novel test systems utilizing ACPA have been developed. Citrullinated vimentin is a very promising autoantigen in RA, and a suitable tool for studying this systemic autoimmune disease. Vimentin is secreted and citrullinated by macrophages in response to apoptosis, or by pro-inflammatory cytokines, such as tumor necrosis factor-alpha ...

  9. Lixisenatide - Wikipedia

    en.wikipedia.org/wiki/Lixisenatide

    Lixisenatide is a peptide made of 44 amino acids, with an amide group on its C terminus. [ 3 ] has been described as "des-38-proline-exendin-4 ( Heloderma suspectum )-(1–39)-peptidylpenta- L -lysyl- L -lysinamide", meaning it is derived from the first 39 amino acids in the sequence of the peptide exendin-4 , that was isolated from the Gila ...

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