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Kagami-Ogata syndrome is a rare genetic disease that is caused by mutations on Maternal chromosome 14 or by paternal UPD(14). [1] The main signs of this disease are: polyhydramnios, narrow bell-shaped thorax, coat-hanger-like ribs, abdominal wall defect, enlarged placenta. [2]
Coxa valga is a deformity of the hip where the angle formed between the head and neck of the femur and its shaft is increased, usually above 135 degrees.. The deformity may develop in children with neuromuscular disorders (i.e. cerebral palsy, spinal dysraphism, poliomyelitis), skeletal dysplasias, and juvenile idiopathic arthritis.
Hip dysplasia may occur at birth or develop in early life. [1] Regardless, it does not typically produce symptoms in babies less than a year old. [3] Occasionally one leg may be shorter than the other. [1] The left hip is more often affected than the right. [3] Complications without treatment can include arthritis, limping, and low back pain. [3]
The collum forms an angle with the shaft in about 130 degrees. This angle is highly variant. In the infant it is about 150 degrees and in old age reduced to 120 degrees on average. An abnormal increase in the angle is known as coxa valga and an abnormal reduction is called coxa vara.
Coxa vara is a deformity of the hip, whereby the angle between the head and the shaft of the femur is reduced to less than 120 degrees. This results in the leg being shortened and the development of a limp .
A 2021 study found that one extra year of life expectancy due to slowed aging equates to $38 trillion in economic gain. The goal of the competition is to extend health span, the number of years ...
Treatment includes supportive measures such as a device to protect the skull and dental care. [5] Surgery may be performed to fix certain bone abnormalities. [4] Life expectancy is generally normal. [3] It affects about one per million people. [1] Males and females are equally commonly affected. [5]
SCFEs are most common in adolescents 11–15 years of age, [6] and affects boys more frequently than girls (male 2:1 female). [2] [4] It is strongly linked to obesity, and weight loss may decrease the risk. [14] Other risk factors include: family history, endocrine disorders, radiation / chemotherapy, and mild trauma.