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Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
A 2020 review noted that about 22 percent of American adults meet the diagnostic criteria for insomnia. This results in feeling sleepy during the day, affecting your mood and ability to do daily ...
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
Primary insomnia is a sleep disorder not attributable to a medical, psychiatric, or environmental cause. [127] There are three main types of primary insomnia. These include psychophysiological, idiopathic insomnia, and sleep state misperception (paradoxical insomnia). [ 124 ]
The causes are varied, including menopause and sleep apnea. See what might keep you up. ... Insomnia is observed frequently among older adults and include waking early, taking longer to fall ...
In a mouse study, researchers found that zolpidem (Ambien), a common sleep aid, could prevent the brain from effectively clearing up 'waste', though it remains unclear whether this could affect ...
Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2] However, somnifacients only benefit transient or short-term insomnia but not chronic insomnia. [ 3 ] It is because somnifacients lack supportive evidence for sleep aids in chronic insomnia, and chronic use of somnifacients leads to many adverse effects .
The possible causes of non-24-hour sleep-wake disorder are 2-fold: (1), extrinsic: isolation from daily light cycles (such as working in an environment completely devoid of natural lighting); [citation needed] and (2), intrinsic: where some condition, such as blindness or malfunctioning biochemical response to light in the subject, prevent ...