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Deep white matter hyperintensities occur deep within white matter, periventricular white matter hyperintensities occur adjacent to the lateral ventricles and subcortical hyperintensities occur in the basal ganglia. [citation needed] Hyperintensities are often seen in auto immune diseases that have effects on the brain. [6]
Head CT showing periventricular white matter lesions. Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults. [1] [2] On MRI, leukoaraiosis changes appear as white matter hyperintensities (WMHs) in T2 FLAIR images.
The lobes of the brain most likely to be injured are the frontal and temporal lobes. [19] Other common locations for DAI include the white matter in the cerebral cortex, the superior cerebral peduncles, [16] basal ganglia, thalamus, and deep hemispheric nuclei.
Researchers analyzing the white matter of superagers over a 5-year period found that despite comparable overall white matter health with typical older adults, superagers exhibited superior ...
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
Structural neuroimaging studies consistently report increased frequency of white matter hyperintensities in people with bipolar. However, whether or not the lesions play a causative role is unknown. It is possible that they are a result of secondary factors, such as the processes underlying an increased risk of cardiovascular disease in bipolar.
SLF I is the dorsal component and originates in the superior and medial parietal cortex, passes around the cingulate sulcus and in the superior parietal and frontal white matter, and terminates in the dorsal and medial cortex of the frontal lobe (Brodmann 6, 8, and 9) and in the supplementary motor cortex (M II).
Hippocampus (Medial Temporal Lobe) Dentate gyrus; Cornu ammonis (CA fields) Cornu ammonis area 1 (CA1) Cornu ammonis area 2 (CA2) Cornu ammonis area 3 (CA3) Cornu ammonis area 4 (CA4) Amygdala (limbic system) (limbic lobe) Central nucleus (autonomic nervous system) Medial nucleus (accessory olfactory system) Cortical and basomedial nuclei (main ...