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Urobilin or urochrome is the chemical primarily responsible for the yellow color of urine. It is a linear tetrapyrrole compound that, along with the related colorless compound urobilinogen , are degradation products of the cyclic tetrapyrrole heme .
Urobilinogen is a yellow by-product of bilirubin reduction. It is formed in the intestines by the bacterial enzyme bilirubin reductase. [1] About half of the urobilinogen formed is reabsorbed and taken up via the portal vein to the liver, enters circulation and is excreted by the kidney.
[6] [7] Urine also contains proteins, hormones, and a wide range of metabolites, [8] varying by what is introduced into the body. [citation needed] The total solids in urine are on average 59 g (2.1 oz) per day per person. [8] Urea is the largest constituent of the solids, constituting more than 50% of the total.
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Stercobilin is a tetrapyrrolic bile pigment and is one end-product of heme catabolism. [1] [2] It is the chemical responsible for the brown color of human feces and was originally isolated from feces in 1932.
It is further processed to become the chemical that gives feces its brown color. [1] Bilirubin is a pigment that results from the breakdown of the heme portion of hemoglobin. The liver conjugates bilirubin, making it water-soluble; and the conjugated form is then excreted in urine as urobilinogen and in the feces as stercobilinogen.
The bilin-binding protein from Pieris brassicae, which was discovered to have a crystal structure, was one of the initial members of the lipocalins protein superfamily, which has since grown significantly. It is a blue pigment protein that can be clearly identified by its amino acid sequence and crystal structure.
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