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The cause of the majority of spinal tumors is currently not known. Primary spinal tumors are associated with a few genetic syndromes. [1] [5] Neurofibromas are associated with neurofibromatosis 1 (NF1). [1] Meningiomas and schwannomas are associated with neurofibromatosis 2 (NF2). [1] Intramedullary hemangioblastomas can be seen in patients ...
Spinal and bulbar muscular atrophy; Spinal cord injury; Spinal cord tumors; Spinal muscular atrophy; Spinal muscular atrophy with respiratory distress type 1 – see Distal spinal muscular atrophy type 1; Spinocerebellar ataxia; Split-brain; Steele–Richardson–Olszewski syndrome – see Progressive supranuclear palsy; Stiff-person syndrome ...
Because each vertebra can cause pain in different areas of the body, the pain from the disease can be sensed in the back, leg, neck area, or even the arms. When the spinal canal begins to lose its gap and gets thinner, it can cause pain in the neck, which can also cause a numb feeling in the arms and hands.
Causes can be bone fragments from a vertebral fracture, a tumor, abscess, ruptured intervertebral disc or other lesion. When acute it can cause a medical emergency independent of its cause, and require swift diagnosis and treatment to prevent long-term disability due to irreversible spinal cord injury .
A tumor near the spinal cord may cause spinal deformity or spinal compression, leading to pain and loss of muscle control or sensation in the legs and/or arms. [4] These tumors may produce certain hormones, which can cause diarrhea, an enlarged clitoris (in females), high blood pressure, increased body hair, and sweating. [4]
Moderate-to-severe cases can cause radicular pain in the legs caused by nerve root compression. [5] The symptoms are usually exacerbated by upright posture and often, but not always, relieved by lying down. Postural headaches can be related to spontaneous spinal cerebrospinal fluid leaks. [6] However, in many patients, dural ectasia is ...
Spinal tumors can be classified into primary tumours or metastatic tumours which originate from or disseminate to the site of compression, respectively. As the tumours surrounding the spinal column grow in size, the spinal canal is narrowed and therefore results in pressure to be exerted directly on the spinal cord and nerve roots.
Causes may include osteoarthritis, rheumatoid arthritis, spinal tumors, trauma, Paget's disease of the bone, scoliosis, spondylolisthesis, and the genetic condition achondroplasia. [3] It can be classified by the part of the spine affected into cervical, thoracic, and lumbar stenosis. [2]