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Mifepristone, and also known by its developmental code name RU-486, is a drug typically used in combination with misoprostol to bring about a medical abortion during pregnancy. [8] This combination is 97% effective [ 9 ] during the first 63 days (9 weeks) of pregnancy , yet effective in the second trimester as well.
Studies show it is as safe to use as common over-the-counter pain relievers like ibuprofen and acetaminophen, and the protocol for medication abortion is used in more than 60 other countries.
Antiglucocorticoid drugs are a class of medications that act to reduce the effects of glucocorticoids, primarily cortisol, in the body. [1] They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome. [2]
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [ 37 ]
The FDA approved mifepristone in 2000 as a safe and effective way to end early pregnancies. There are rare occasions when mifepristone can cause dangerous, excessive bleeding that requires ...
Pro-choice advocates argue that mifepristone is safe, citing numerous studies showing its safety and effectiveness, including for treating miscarriages, from as far back as 1988.
Medication abortion is the preferred method of ending pregnancy in the U.S., and one of the two drugs used — mifepristone — will now go in front of the U.S. Supreme Court next year. Demand for ...
WASHINGTON (Reuters) -The U.S. government on Monday appealed a Texas judge's decision to suspend the Food and Drug Administration's 23-year-old approval of a key abortion drug, saying the ruling ...