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Purkinje fibers are a unique cardiac end-organ. Further histologic examination reveals that these fibers are split in ventricles walls. The electrical origin of atrial Purkinje fibers arrives from the sinoatrial node. Given no aberrant channels, the Purkinje fibers are distinctly shielded from each other by collagen or the cardiac skeleton.
The Purkinje layer of the cerebellum, which contains the cell bodies of the Purkinje cells and Bergmann glia, express a large number of unique genes. [9] Purkinje-specific gene markers were also proposed by comparing the transcriptome of Purkinje-deficient mice with that of wild-type mice. [10]
Each climbing fiber will form synapses with 1-10 Purkinje cells. Early in development, Purkinje cells are innervated by multiple climbing fibers, but as the cerebellum matures, these inputs gradually become eliminated resulting in a single climbing fiber input per Purkinje cell.
There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum.The nuclei are the fastigial, globose, emboliform, and dentate nuclei.. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus.
These parallel fibers form thousands of excitatory granule-cell–Purkinje-cell synapses onto the intermediate and distal dendrites of Purkinje cells using glutamate as a neurotransmitter. Layer 4 granule cells of the cerebral cortex receive inputs from the thalamus and send projections to supragranular layers 2–3, but also to infragranular ...
Granule-cell to Purkinje-cell synapses or gcPc synapses are the junctions that form the synapse in the cerebellum between granule cells and Purkinje cells. [1] These synapses are thought to be a storage site for the information that is required for motor coordination and their misfunctioning is involved with some movement disorders . [ 2 ]
Purkinje images are reflections of objects from the structure of the eye. They are also known as Purkinje reflexes and as Purkinje–Sanson images. At least four Purkinje images are usually visible in the normal eye. The first Purkinje image (P1) is the reflection from the outer surface of the cornea. The second Purkinje image (P2) is the ...
Histology at ucsd.edu Archived September 18, 2020, at the Wayback Machine; Histology at umdnj.edu "Chapter 1: The Muscle Spindle and the Central Nervous System". Neuromuscular Reeducation with Electromyometric Feedback (PDF). Advanced Therapy Institute. Archived from the original (PDF) on December 3, 2013