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  2. In vivo - Wikipedia

    en.wikipedia.org/wiki/In_vivo

    In microbiology, in vivo is often used to refer to experimentation done in a whole organism, rather than in live isolated cells, for example, cultured cells derived from biopsies. In this situation, the more specific term is ex vivo. Once cells are disrupted and individual parts are tested or analyzed, this is known as in vitro. [citation needed]

  3. Models of scientific inquiry - Wikipedia

    en.wikipedia.org/wiki/Models_of_scientific_inquiry

    When a hypothesis has survived a sufficient number of tests, it may be promoted to a scientific theory. A theory is a hypothesis that has survived many tests and seems to be consistent with other established scientific theories. Since a theory is a promoted hypothesis, it is of the same 'logical' species and shares the same logical limitations.

  4. Scientific theory - Wikipedia

    en.wikipedia.org/wiki/Scientific_theory

    A scientific theory is an explanation of an aspect of the natural world that can be or that has been repeatedly tested and has corroborating evidence in accordance with the scientific method, using accepted protocols of observation, measurement, and evaluation of results.

  5. Animal testing - Wikipedia

    en.wikipedia.org/wiki/Animal_testing

    Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...

  6. Live-cell imaging - Wikipedia

    en.wikipedia.org/wiki/Live-cell_imaging

    Biological systems exist as a complex interplay of countless cellular components interacting across four dimensions to produce the phenomenon called life. While it is common to reduce living organisms to non-living samples to accommodate traditional static imaging tools, the further the sample deviates from the native conditions, the more likely the delicate processes in question will exhibit ...

  7. In silico - Wikipedia

    en.wikipedia.org/wiki/In_silico

    For example, in 2007 researchers developed an in silico model of tuberculosis to aid in drug discovery, with the prime benefit of its being faster than real time simulated growth rates, allowing phenomena of interest to be observed in minutes rather than months. [9]

  8. Immunostaining - Wikipedia

    en.wikipedia.org/wiki/Immunostaining

    Micrograph of a GFAP immunostained section of a brain tumour.. In biochemistry, immunostaining is any use of an antibody-based method to detect a specific protein in a sample. . The term "immunostaining" was originally used to refer to the immunohistochemical staining of tissue sections, as first described by Albert Coons in 1941.

  9. Molecular imaging - Wikipedia

    en.wikipedia.org/wiki/Molecular_imaging

    PET, MRI, and overlaid images of a human brain. Positron emission tomography (PET) is a nuclear medicine imaging technique which produces a three-dimensional image or picture of functional processes in the body. The theory behind PET is simple enough. First a molecule is tagged with a positron emitting isotope.