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Neonatal meningitis is a serious medical condition in infants that is rapidly fatal if untreated.Meningitis, an inflammation of the meninges, the protective membranes of the central nervous system, is more common in the neonatal period (infants less than 44 days old) than any other time in life, and is an important cause of morbidity and mortality globally.
Although meningitis is a notifiable disease in many countries, the exact incidence rate is unknown. [22] In 2013 meningitis resulted in 303,000 deaths – down from 464,000 deaths in 1990. [86] In 2010 it was estimated that meningitis resulted in 420,000 deaths, [87] excluding cryptococcal meningitis. [42]
Bacteria found in the maternal gastrointestinal or gastrourinary tracts can commonly lead to neonatal infection. Bacterial infections may present as fetal distress at birth (including signs of tachycardia, temperature instability or difficulty breathing), neonatal sepsis, or neonatal meningitis.
Neonatal meningitis is a particular classification by age. By anatomical site. Brain abscess, Epidural abscess, including spinal epidural and cranial epidural;
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
S.agalactiae neonatal meningitis does not present with the hallmark sign of adult meningitis, a stiff neck. Instead, it presents with nonspecific symptoms, such as fever, vomiting, and irritability, and can consequently lead to a late diagnosis. Hearing loss and mental impairment can be a long-term consequence of GBS meningitis. [4] [21]
Fatal neonatal infections by GBS are more frequent among premature infants. [3] [30] [31] [37] GBS LOD affects infants from 7 days to 3 months of age and is more likely to cause bacteremia or meningitis. LOD can be acquired from the mother or from environmental sources. Hearing loss and mental impairment can be a long-term sequela of GBS ...
Neonatal meningitis is the most common presentation of Elizabethkingia for children. Recent studies suggest that approximately 31% of children that have Elizabethkingia pass away from the infection, with an average life expectancy of 27 days from onset of symptoms. [12]