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  2. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    The sugar pucker which determines the shape of the a-helix, whether the helix will exist in the A-form or in the B-form, occurs at the C2'-endo. [13] A-DNA, is a form of the DNA duplex observed under dehydrating conditions. It is shorter and wider than B-DNA. RNA adopts this double helical form, and RNA-DNA duplexes are mostly A-form, but B ...

  3. A-DNA - Wikipedia

    en.wikipedia.org/wiki/A-DNA

    In one study, the characteristic C3'-endo pucker is found on the first three sugars of the DNA strand, while the last three sugars have a C2'-endo pucker, like B-DNA. [2] These intermediates can form in aqueous solutions when the cytosine bases are methylated or brominated, altering the conformation.

  4. Deoxyribose - Wikipedia

    en.wikipedia.org/wiki/Deoxyribose

    In aqueous solution, deoxyribose primarily exists as a mixture of three structures: the linear form H−(C=O)−(CH 2)−(CHOH) 3 −H and two ring forms, deoxyribofuranose ("C3′-endo"), with a five-membered ring, and deoxyribopyranose ("C2′-endo"), with a six-membered ring. The latter form is predominant (whereas the C3′-endo form is ...

  5. Nucleic acid double helix - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_double_helix

    The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...

  6. RNA world - Wikipedia

    en.wikipedia.org/wiki/RNA_world

    The hydroxyl group also forces the ribose into the C3'-endo sugar conformation unlike the C2'-endo conformation of the deoxyribose sugar in DNA. This forces an RNA double helix to change from a B-DNA structure to one more closely resembling A-DNA.

  7. Lectin pathway - Wikipedia

    en.wikipedia.org/wiki/Lectin_pathway

    Structure of mannose in its α-D mannopyranose form. Mannan is a polymer of mannose.. The lectin pathway or MBL pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, [1] in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade.

  8. Z-DNA - Wikipedia

    en.wikipedia.org/wiki/Z-DNA

    The Z-DNA structure. Proteopedia Z-DNA. Z-DNA is one of the many possible double helical structures of DNA.It is a left-handed double helical structure in which the helix winds to the left in a zigzag pattern, instead of to the right, like the more common B-DNA form.

  9. Complement component 3 - Wikipedia

    en.wikipedia.org/wiki/Complement_component_3

    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals and contributes to innate immunity .