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  2. Long-acting beta-adrenoceptor agonist - Wikipedia

    en.wikipedia.org/wiki/Long-acting_beta...

    The proposed mechanism is that while LABAs relieve asthma symptoms, they can also promote bronchial inflammation and sensitivity without warning. [23] On February 18, 2011, the FDA issued a safety alert for long-acting β agonists. [24]

  3. Beta2-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta2-adrenergic_agonist

    Overuse of β 2 agonists and asthma treatment without proper inhaled corticosteroid use has been associated with an increased risk of asthma exacerbations and asthma-related hospitalizations. [8] The excipients, in particular sulfite, could contribute to the adverse effects.

  4. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    By treating asthma with optically pure (R)-salbutamol the risk of side effects, such as nervous system stimulatory effects and cardiac arrhythmia, can be minimized. [20] There are several routes for enantioselective synthesis , as well as methods for synthesis of the racemic mixture followed by chiral resolution .

  5. Beta-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta-adrenergic_agonist

    In general, pure beta-adrenergic agonists have the opposite function of beta blockers: beta-adrenoreceptor agonist ligands mimic the actions of both epinephrine- and norepinephrine- signaling, in the heart and lungs, and in smooth muscle tissue; epinephrine expresses the higher affinity.

  6. Beta-2 adrenergic antagonist - Wikipedia

    en.wikipedia.org/wiki/Beta-2_adrenergic_antagonist

    A Beta-2 adrenergic antagonist (β 2-adrenoceptor antagonist) is an adrenergic antagonist which blocks the beta-2 adrenergic receptors of cells, with either high specificity (an antagonist which is selective for β 2 adrenoceptors) like Butaxamine and ICI-118,551, or non-specifically (an antagonist for β 2 and for β 1 or β 3 adrenoceptors) like the non-selective betablocker Propranolol.

  7. Adrenergic blocking agent - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_blocking_agent

    The combination of beta blockers and antihypertensive drugs will work on different mechanism to lower blood pressure. [17] For example, the co-administration of beta-1 blocker atenolol and ACE inhibitor lisinopril could produce a 50% larger reduction in blood pressure than using either drug alone. [18]

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