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As an example, of the 91,523 women in the Nurses' Health Study who did not have cancer at baseline and who were followed for 14 years, 2,341 women had developed breast cancer by 1993. Several studies have used standard cohort analyses to study precursors to breast cancer, e.g. use of hormonal contraceptives, [ 3 ] which is a covariate easily ...
Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...
In retrospective CAA studies, a classifier is trained with machine learning algorithms using existing data. The performance of the classifier is then assessed using the same data. Different approaches are used to do this (e.g., k-Fold cross-validation, leave-one-out cross-validation). The main shortcoming of judging the quality (sensitivity ...
A "prospective cohort" defines the groups before the study is done, while historical studies, which are sometimes referred to as "retrospective cohort", define the grouping after the data is collected. Examples of a retrospective cohort are Long-Term Mortality after Gastric Bypass Surgery [13] and The Lothian Birth Cohort Studies. [14]
In qualitative research, a member check, also known as informant feedback or respondent validation, is a technique used by researchers to help improve the accuracy, credibility, validity, and transferability (also known as applicability, internal validity, [1] or fittingness) of a study. [2]
Utilization management is "a set of techniques used by or on behalf of purchasers of health care benefits to manage health care costs by influencing patient care decision-making through case-by-case assessments of the appropriateness of care prior to its provision," as defined by the Institute of Medicine [1] Committee on Utilization Management by Third Parties (1989; IOM is now the National ...
Verification is intended to check that a product, service, or system meets a set of design specifications. [6] [7] In the development phase, verification procedures involve performing special tests to model or simulate a portion, or the entirety, of a product, service, or system, then performing a review or analysis of the modeling results.
A retrospective cohort study, also called a historic cohort study, is a longitudinal cohort study used in medical and psychological research. A cohort of individuals that share a common exposure factor is compared with another group of equivalent individuals not exposed to that factor, to determine the factor's influence on the incidence of a ...