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This is a list of adverse effects of the antidepressant trazodone, ... Insomnia; Dream disorder; ... Rare (<0.1%) adverse effects include: Urinary retention;
Trazodone is usually used at a dosage of 150 to 300 mg/day for the treatment of depression. [17] [13] Lower doses have also been used to augment other antidepressants or when initiating therapy. [17] [13] Higher doses, up to 600 mg/day, have been used in more severe cases of depression (in hospitalized patients, for example). [29]
Niaprazine (Nopron) – a drug related to this group but does not inhibit the reuptake of serotonin or the other monoamines. Medifoxamine (Clédial, Gerdaxyl) – could perhaps technically be said to belong to this group, as it is a serotonin–dopamine reuptake inhibitor and 5-HT 2A and 5-HT 2C receptor antagonist, but not grouped as such. [1]
Used off-label for anxiety, Alzheimer's disease, bulimia, fibromyalgia and PTSD, trazodone is also commonly used to treat insomnia at a lower dosage than for depression.
The most common adverse effects include nausea, diarrhea, vomiting, and insomnia. [ 5 ] After a one-year, open-label study assessing the safety and tolerability of vilazodone in people with major depressive disorder, the most common adverse effects were diarrhea (35.7%), nausea (31.6%), and headache (20.0%); greater than 90% of these adverse ...
The rate of dosage reduction is best carried out so as to minimize the symptoms' intensity and severity. Anecdotally, a slow rate of reduction may reduce the risk of developing a severe protracted syndrome. Long half-life benzodiazepines like diazepam [1] or chlordiazepoxide are preferred to minimize rebound effects and are available in low ...
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