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A cortical column is a group of neurons forming a cylindrical structure through the cerebral cortex of the brain perpendicular to the cortical surface. [1] The structure was first identified by Vernon Benjamin Mountcastle in 1957. He later identified minicolumns as the basic units of the neocortex which were arranged into columns. [2]
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.
The cortex is the outer layer of the brain and is composed of up to six layers. Neurons formed in the ventricular zone migrate to their final locations in one of the six layers of the cortex. [ 1 ] The process occurs from embryonic day 10 to 17 in mice and between gestational weeks seven to 18 in humans.
Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells, which, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the ...
A 2-D model of cortical sensory homunculus. A cortical homunculus (from Latin homunculus 'little man, miniature human' [1] [2]) is a distorted representation of the human body, based on a neurological "map" of the areas and portions of the human brain dedicated to processing motor functions, and/ or sensory functions, for different parts of the body.
These tracts are in turn modulated by various parts of the central nervous system, including the nigrostriatal pathway, the basal ganglia, the cerebellum, the vestibular nuclei, and different sensory areas of the cerebral cortex. All of these regulatory components can be considered part of the extrapyramidal system, in that they modulate motor ...
The term limbic system was introduced in 1952 by Paul MacLean to describe the set of structures that line the deep edge of the cortex (Latin limbus meaning border): [17] These include the hippocampus, cingulate cortex, olfactory cortex, and amygdala. Paul MacLean later suggested that the limbic structures comprise the neural basis of emotion.
The allocortex (from Latin allo-, meaning other, and cortex, meaning bark or crust), or heterogenetic cortex, and neocortex are the two types of cerebral cortex in the brain. In the human brain , the allocortex is the much smaller area of cortex taking up just 10%; the neocortex takes up the remaining 90%. [ 1 ]