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Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have dmoad activity ...
Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection. [1] The main risk factors for osteoarthritis are age [2] [3] and body mass index, [4] [3] as such, OA is predominantly considered a disease of ...
Editor’s note: Before beginning any new exercise program, consult your doctor.Stop immediately if you experience pain. Chances are you know someone who has had a total knee replacement. The ...
Osteoarthritis is often the cause of knee pain, especially for women and older adults, according to the Arthritis Foundation. But sore knees may also result from an injury, weak or tight muscles ...
A new study looks into whether all that crackling should be a wake-up call for your joint health. Here’s what to know about creaky knees and arthritis risk.
Conventional DMARDs are known to be the first-line treatment for rheumatoid arthritis. [9] Treatment can be a monotherapy or in combination with other anti-arthritic medications. Common DMARDs include oral methotrexate, leflunomide, or sulfasalazine. Conventional DMARDs have a slow onset of action and can take 2–3 months to exhibit effect. [9]
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