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Phenibut is used in Russia, Ukraine, Belarus and Latvia as a pharmaceutical drug to treat anxiety and to improve sleep (e.g., in the treatment of insomnia). [5] [6] It is also used for various other indications, including the treatment of asthenia, depression, alcoholism, alcohol withdrawal syndrome, post-traumatic stress disorder, stuttering, tics, vestibular disorders, Ménière's disease ...
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Phenibut, like other GABA B agonists, is also sometimes used by bodybuilders to increase the human growth hormone. Reuters reported on 25 March 2010 that " Pfizer Inc violated a United States racketeering law by improperly promoting the epilepsy drug Neurontin (gabapentin).
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As part of the plea, [the defendant] has agreed to forfeit $2.4 million. [The defendant] has also agreed to forfeit all tianeptine, adrafinil, phenibut, and racetams seized by the FDA and Customs and Border Protection. FDA has not approved drugs containing tianeptine, adrafinil, phenibut, and racetams for use in the United States.
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The drug is a GABA analogue and is closely related to baclofen (β-(4-chlorophenyl)-GABA), tolibut (β-(4-methylphenyl)-GABA), and phenibut (β-phenyl-GABA). [1] It is less potent as a GABA B receptor agonist than baclofen but more potent than phenibut.