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The disease generally affects only one of the larger weight bearing joints (hip, ankle, knee) – although the elbow, and wrist can also be affected. It rarely involves the temporomandibular joint (TMJ) and most publications are case reports. [3] Synovial chondromatosis occurs twice as commonly in males as females and usually in their forties.
Synovial osteochondromatosis (SOC) (synonyms include synovial chondromatosis, primary synovial chondromatosis, synovial chondrometaplasia) is a rare disease that creates a benign change or proliferation in the synovium or joint-lining tissue, which changes to form bone-forming cartilage. In most occurrences, there is only one joint affected ...
About 20% of people with rheumatoid arthritis develop rheumatoid nodules, which are linked to more severe erosive disease in those patients. [2] The nodules are more common in men, typically manifest in the fifth decade of life, and are primarily found on extensor surfaces like the backs of the fingers and elbows, though they can occur anywhere.
Surgery has been the most common form of treatment for both localized [3]: 101 [5]: 361 and diffuse TGCT. [ 3 ] : 103 [ 5 ] : 361 [ 10 ] : 1 After surgery, patients may receive physical therapy in order to help rehabilitate affected joints.
The redness starts to fade and it gradually becomes softer and smaller until it disappears. Each nodule usually heals completely without scarring over the course of about two weeks. [3] [4] Joint pain and inflammation sometimes continue for several weeks or months after the nodules appear. [5] Less common variants of erythema nodosum include:
Carpal tunnel surgery is usually considered after other treatment options have failed, Melamed says. Other, less invasive treatments, like splinting and steroid injections, are typically tried first.
Complications of treatment may include joint stiffness and scar formation. [26] Recurrence of the lesion is more common following excision of a volar ganglion cyst in the wrist. Incomplete excision that fails to include the stalk or pedicle also may lead to recurrence, as will failing to execute a layered closure of the incision.
Central nervous system nodules. Like cardiac nodules, nodules developing in the central nervous system is also relatively rare. Most reports of nodule growth on the central nervous system also presented with severe stages of erosive joint diseases. [22] Generally, these nodules can be detected through MRI and confirmed through biopsies.
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