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  2. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.

  3. Serum iron - Wikipedia

    en.wikipedia.org/wiki/Serum_iron

    Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin and freely circulate in the blood. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia and other problems. 65% of the iron in the body is bound up in hemoglobin molecules in red blood cells.

  4. Hereditary haemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_haemochromatosis

    Normally, HFE facilitates the binding of transferrin, which is iron's carrier protein in the blood. Transferrin levels are typically elevated at times of iron depletion (low ferritin stimulates the release of transferrin from the liver). When transferrin is high, HFE works to increase the intestinal release of iron into the blood.

  5. Transferrin saturation - Wikipedia

    en.wikipedia.org/wiki/Transferrin_saturation

    For instance, a value of 15% means that 15% of iron-binding sites of transferrin are being occupied by iron. The three results are usually reported together. A low transferrin saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis.

  6. Hemochromatosis type 4 - Wikipedia

    en.wikipedia.org/wiki/Hemochromatosis_type_4

    This iron unavailability potentially leads to mild anemia in type 4A hemochromatosis patients because iron is necessary for hemoglobin synthesis, and red blood cells have a relatively high turnover rate. [4] Over time, iron stores increase, and individuals with type 4A hemochromatosis may develop hepatic fibrosis. [3]

  7. 7 Supplement Combos You Should Never Take Together ... - AOL

    www.aol.com/7-supplement-combos-never-together...

    In particular, iron supplements with 25 mg of iron or more could be problematic for zinc levels. Although high doses of iron are very common when treating iron deficiency, they can reduce zinc ...

  8. Iron deficiency in adults may be more common than thought ...

    www.aol.com/news/iron-deficiency-adults-may-more...

    An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood levels, a condition known as absolute iron deficiency, while 15% had the right iron levels but ...

  9. Iron poisoning - Wikipedia

    en.wikipedia.org/wiki/Iron_poisoning

    In general, levels below 350mcg/dL are associated with more mild iron poisoning while upper levels above 500mcg/dL are associated with more severe iron poisoning. [3] Measuring electrolyte levels, kidney function, serum glucose, liver function tests (enzymes and bilirubin), complete blood count, clotting time via prothrombin and partial ...

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