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Cisplatin ([Pt (NH3)2Cl2) is a widely used anticancer drug. Ammonia is a ligand forming metal ammine complexes. For historical reasons, ammonia is named ammine in the nomenclature of coordination compounds. One notable ammine complex is cisplatin (Pt (NH3)2Cl2, a widely used anticancer drug.
Infobox references. Ammonium is a modified form of ammonia that has an extra hydrogen atom. It is a positively charged (cationic) molecular ion with the chemical formula NH+ 4 or [NH4]+. It is formed by the addition of a proton (a hydrogen nucleus) to ammonia (NH3).
The molecule adopts a structure similar to that of ethane, with which it is isoelectronic. The B−N distance is 1.58(2) Å. The B−H and N−H distances are 1.15 and 0.96 Å, respectively. Its similarity to ethane is tenuous since ammonia borane is a solid and ethane is a gas: their melting points differing by 284 °C.
Ammonia solution, also known as ammonia water, ammonium hydroxide, ammoniacal liquor, ammonia liquor, aqua ammonia, aqueous ammonia, or (inaccurately) ammonia, is a solution of ammonia in water. It can be denoted by the symbols NH 3 (aq). Although the name ammonium hydroxide suggests a salt with the composition [NH+4] [OH−], it is actually ...
Amine. In chemistry, amines (/ ə ˈ m iː n, ˈ æ m iː n /, [1] [2] UK also / ˈ eɪ m iː n / [3]) are compounds and functional groups that contain a basic nitrogen atom with a lone pair.Formally, amines are derivatives of ammonia (NH 3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group [4] (these may respectively be called alkylamines ...
Cisplatin, PtCl 2 (NH 3) 2, is a coordination complex of platinum(II) with two chloride and two ammonia ligands.It is one of the most successful anticancer drugs. A coordination complex is a chemical compound consisting of a central atom or ion, which is usually metallic and is called the coordination centre, and a surrounding array of bound molecules or ions, that are in turn known as ligands ...
Molecular geometry. Geometry of the water molecule with values for O-H bond length and for H-O-H bond angle between two bonds. Molecular geometry is the three-dimensional arrangement of the atoms that constitute a molecule. It includes the general shape of the molecule as well as bond lengths, bond angles, torsional angles and any other ...
Metal ammine complex. Ball-and-stick model of the tetraamminediaquacopper (II) cation, [Cu (NH3)4(H2O)2]2+. In coordination chemistry, metal ammine complexes are metal complexes containing at least one ammonia (NH3) ligand. "Ammine" is spelled this way for historical reasons; [1] in contrast, alkyl or aryl bearing ligands are spelt with a ...