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Trisomy 21. Down syndrome (also known by the karyotype 47,XX,+21 for females and 47,XY,+21 for males) [98] is mostly caused by a failure of the 21st chromosome to separate during egg or sperm development, known as nondisjunction. [91] As a result, a sperm or egg cell is produced with an extra copy of chromosome 21; this cell thus has 24 ...
Mongolian idiocy. The obsolete medical terms Mongolian idiocy and Mongolism referred to a specific type of mental deficiency, associated with the genetic disorder now known as Down syndrome. The obsolete term for a person with this syndrome was called a Mongolian idiot. In the 21st century, these terms are no longer used as medical terminology ...
John Langdon Down, whose name is used for the condition today, coined the term "imbecile of the Mongoloid type" in 1856, labelling those with the condition the "Mongolian type of Idiot" as part of Down's wider theory that it was possible to classify different types of conditions by supposed ethnic characteristics. Despite his comparison, Down ...
Genetics of Down syndrome. Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on chromosome 21, either in whole (trisomy 21) or part (such as due to translocations). The effects of the extra copy varies greatly from individual to individual, depending on the extent of the extra copy ...
Down syndrome is a genetic disorder that often results in distinct physical differences and intellectual disability. According to the Centers for Disease Control, each year about 6,000 babies are ...
Mongoloid (/ ˈmɒŋɡəˌlɔɪd /) [ 1 ] is an obsolete racial grouping of various peoples indigenous to large parts of Asia, the Americas, and some regions in Europe and Oceania. The term is derived from a now-disproven theory of biological race. [ 2 ] In the past, other terms such as " Mongolian race", "yellow", "Asiatic" and " Oriental ...
Lists. v. t. e. The following is a list of terms, used to describe disabilities or people with disabilities, which may carry negative connotations or be offensive to people with or without disabilities. Some people consider it best to use person-first language, for example "a person with a disability" rather than "a disabled person." [1]
Here are amazing individuals with Down syndrome who are breaking the barriers of disability stigmas. Edward Barbanell. A comedian who has been in hit productions such as Workaholics and The Ringer ...