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Paroxetine, sold under the brand name Paxil among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Contents. Development and discovery of SSRI drugs. Selective serotonin reuptake inhibitors, or serotonin-specific re-uptake inhibitor (SSRIs), are a class of chemical compounds that have application as antidepressants and in the treatment of depression and other psychiatric disorders. SSRIs are therapeutically useful in the treatment of panic ...
Lunesta (eszopiclone) – a non-benzodiazepine hypnotic. Luvox (fluvoxamine) – an antidepressant of the SSRI class. Loxitane (loxapine) – an antipsychotic used in the treatment of mood disorders and schizophrenia. Lyrica (pregabalin) – treats nerve and muscle pain, including fibromyalgia. It can also treat seizures.
Coursera Inc. (/ kərˈsɛrə /) is an American global massive open online course provider. It was founded in 2012 [2][3] by Stanford University computer science professors Andrew Ng and Daphne Koller. [4] Coursera works with universities and other organizations to offer online courses, certifications, and degrees in a variety of subjects.
Study 329 was a clinical trial which was conducted in North America from 1994 to 1998 to study the efficacy of paroxetine, an SSRI anti-depressant, in treating 12- to 18-year-olds diagnosed with major depressive disorder. Led by Martin Keller, then professor of psychiatry at Brown University, and funded by the British pharmaceutical company ...
The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect. As a consequence, there is some controversy over which treatments actually belong in this class.
Very common. Very common (10-100% incidence) adverse effects include: Nausea. Sexual dysfunction (including anorgasmia (difficulty achieving an orgasm), erectile dysfunction, genital anaesthesia, ejaculation disorder, loss of libido etc.). Paroxetine is associated with a higher rate of sexual dysfunction than other SSRIs. [ 5][page needed]
Paroxetine may produce discontinuation-related symptoms at a greater rate than other SSRIs, though qualitatively similar effects have been reported for all SSRIs. [ 174 ] [ 175 ] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from ...