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ACR score is a scale to measure change in rheumatoid arthritis symptoms. [1] It is named after the American College of Rheumatology. The ACR score is more often used in clinical trials than in doctor patient-relationships, as it allows a common standard between researchers. Different degrees of improvement are referred to as ACR20, ACR50, ACR70.
About 230 subjects with moderate to severe rheumatoid arthritis were enrolled into the Phase II arthritis study, which examined the Company’s candidate drug, Natrunix, in combination with methotrexate (MTX). The study’s primary endpoint was the American College of Rheumatology (ACR) 20 response rate after 12 weeks of treatment.
NX-5948 was well-tolerated in all patient populations and across all doses tested from 50 to 600 mg daily. At IWWM-12, in the nine efficacy-evaluable WM patients treated with NX-5948, an ORR of 77.8% was observed with increasing depth of response over time, supporting continued development of NX-5948 for this indication.
Attenuation-to-crosstalk ratio (ACR) is a parameter that is measured when testing a communication link, which represents the overall performance of the cable. [1] AcR is a mathematical formula that calculates the ratio of attenuation to near-end crosstalk for each combination of cable pairs. [ 2 ]
In a comparative study (in 2007), various detection kits had a sensitivity between 69.6% and 77.5% and a specificity between 87.8% and 96.4%. [12] Despite the excellent performance of these immunoassays, for example CCP-assays, they only provide a sensitivity comparable with that of rheumatoid factor (RF).
The American College of Rheumatology (ACR; [1] until 1985 called American Rheumatism Association [2]) is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocacy and practice support relating to the care of people with arthritis and rheumatic and musculoskeletal diseases.
Rate of SLE varies between countries from 20 to 70 per 100,000. [2] Women of childbearing age are affected about nine times more often than men. [5] While it most commonly begins between the ages of 15 and 45, a wide range of ages can be affected. [1] [2] Those of African, Caribbean, and Chinese descent are at higher risk than those of European ...
The ACR is derived from data generated by SSTs, as so falls victim to the same errors and limitations. These limitations are described in detail in literature [ 10 ] Using point estimates such as NOECs/LOECs reduces a data set containing many values down to an isometric, removing the rich visual information that allows the researcher to assess ...