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2. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Sildenafil and tadalafil are also indicated for the treatment of some subtypes of pulmonary hypertension, while tadalafil is also licensed for the treatment of benign prostatic hyperplasia. [1] PDE5 inhibitors have been used as a second line therapy in severe cases of Raynaud phenomenon when it is related to systemic sclerosis per The European ...

3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   Other PDE5 inhibitors, such as sildenafil (Viagra), vardenafil (Levitra), and avanafil (Stendra), will interact with Cialis. ... Tadalafil Side Effects for Benign Prostatic Hyperplasia (BPH)

4. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

   www.aol.com/tadalafil-ultimate-guide-dosages...

   Tadalafil for the symptoms of benign prostatic hyperplasia (BPH) Tadalafil for pulmonary arterial hypertension (PAH) ... The prescription drug is a PDE5 inhibitor, meaning it blocks ...

5. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   The PDE5 inhibitors sildenafil, vardenafil and tadalafil are competitive and reversible inhibitors of cGMP hydrolysis by the catalytic side of PDE5. The structures of vardenafil and sildenafil are similar, they both contain similar structured purine ring of cGMP that contributes their features to act as a competitive inhibitor of PDE5.

6. List of phosphodiesterase inhibitors - Wikipedia

   en.wikipedia.org/wiki/List_of_phosphodiesterase...

   This page was last edited on 9 February 2024, at 00:17 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

7. Cialis and Alcohol: Is it Safe?

   www.aol.com/cialis-alcohol-safe-115800912.html

   PDE5 inhibitors like Cialis are the first line of treatment for ED. ... like a history of heart problems, before taking PDE5 inhibitors for ED or benign prostatic hyperplasia (BPH). ...

8. cGMP-specific phosphodiesterase type 5 - Wikipedia

   en.wikipedia.org/wiki/CGMP-specific...

   8654 242202 Ensembl ENSG00000138735 ENSMUSG00000053965 UniProt O76074 Q8CG03 RefSeq (mRNA) NM_033437 NM_001083 NM_033430 NM_153422 RefSeq (protein) NP_001074 NP_236914 NP_246273 NP_700471 Location (UCSC) Chr 4: 119.49 – 119.63 Mb Chr 3: 122.52 – 122.65 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cyclic guanosine monophosphate-specific phosphodiesterase type 5 is an enzyme (EC ...

9. Is It Safe to Take Cialis Daily? - AOL

   www.aol.com/safe-cialis-daily-115900442.html

   What is Cialis (Tadalafil)? Like other ED medications, Cialis is a PDE5 inhibitor.It works by blocking the effects of PDE5, or cGMP-specific phosphodiesterase type 5 — an enzyme that’s ...