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Some vitamins such as vitamins ADEK are toxic in high doses, [69] including niacin (B 3), [70] cholecalciferol (D) [71] and tocopherol (E). [72] The view of the medical community is that there is no evidence for the efficacy of Orthomolecular medicine as a treatment for cancer, [ 6 ] and that high vitamin doses may – on the contrary ...
Orthomol (full name: Orthomol pharmazeutische Vertriebs GmbH) is a family business based in Langenfeld, North Rhine-Westphalia, Germany. [3] It was founded by Kristian Glagau in 1991 and is now managed by his son Nils together with Michael Schmidt. [4] [5] Orthomol is active in the production of over-the-counter micronutrient supplements.
Histadelia is a condition hypothesised by Carl Pfeiffer [24] [25] to involve elevated serum levels of histamine and basophils, [4] which he says can be treated with methionine and vitamin B 6 megadoses. [26]
The Journal of Orthomolecular Medicine is not indexed by MEDLINE, a database of biomedical literature.Journals are selected for MEDLINE by the National Library of Medicine based on scope and coverage, quality of content, quality of editorial work, intended audience, quality of the layout, printing, graphics, and illustrations. [6]
Vitamins have diverse biochemical functions. Vitamin A acts as a regulator of cell and tissue growth and differentiation. Vitamin D provides a hormone-like function, regulating mineral metabolism for bones and other organs. The B complex vitamins function as enzyme cofactors (coenzymes) or the precursors for them.
Some vitamins have toxic effects when consumed in excess amounts and certain vitamers have a greater potential for toxicity compared to other forms of the same vitamin. For example, hypervitaminosis A is a toxicity syndrome caused by excess consumption of retinoid vitamers of vitamin A such as retinol, retinal, and retinoic acid. [ 1 ]