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Medical use of arsenic trioxide refers to the use of arsenic trioxide (Latin: Arsenum trioxydatum, [1] also known as "arsenic") as an chemotherapeutic agent in the treatment of acute promyelocytic leukemia. Arsenic trioxide has orphan drug status [2] and is available as the pharmaceutical preparation Trisenox.
Medical use of alkaloid-containing plants has a long history, and, thus, when the first alkaloids were isolated in the 19th century, they immediately found application in clinical practice. [206] Many alkaloids are still used in medicine, usually in the form of salts widely used including the following: [ 14 ] [ 207 ]
It is a semifluorinated alkane. [4] Perfluorohexyloctane has been available in multiple markets since 2015 under the brand names Evotears and Novatears, [5] and was additionally approved for medical use in the United States in May 2023 under the brand name Miebo.
PKS uses coenzyme-A thioester to catalyze the reaction and modify the substrates by selectively reducing the β carbonyl to the hydroxyl (Ketoreductase, KR), the alkene (Dehydratase, DH), and the alkane (Enoyl Reductase, ER). PKS-I can also methylate the α carbon of the substrate.
In particular, medicinal chemistry in its most common practice—focusing on small organic molecules—encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the discovery and development of new ...
Liquid paraffin, also known as paraffinum liquidum, paraffin oil, liquid paraffin oil or Russian mineral oil, is a very highly refined mineral oil used in cosmetics and medicine. Cosmetic or medicinal liquid paraffin should not be confused with the paraffin (i.e. kerosene) used as a fuel.
The first medical use of fumaric acid was described in 1959 by Walter Schweckendiek, a German chemist, [15] and was a topical formulation for psoriasis. The Swiss company Fumapharm eventually brought Fumaderm, an oral formulation of dimethyl fumarate (along with some monoesters) to market for psoriasis in Germany in 1994.
Alcohols applied to the skin are used to disinfect skin before a needle stick and before surgery. [2] They may also be used as a hand sanitizer; [2] to clean other areas; [2] and in mouthwashes. [3] [4] [5] Taken by mouth or injected into a vein, ethanol is used to treat methanol or ethylene glycol toxicity when fomepizole is not available. [1]