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Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. [2] [3] It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. [3] It is used as an ear drop or eye drop. [2] [3]
ATC code S01 Ophthalmologicals is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Other serious side effects may include fungal infections, anaphylaxis, and muscle weakness. [1] It is unclear if use during pregnancy is safe for the baby. [1] Polymyxin B works by breaking down the cytoplasmic membrane which generally results in bacterial cell death. [1] Polymyxin B was approved for medical use in the United States in 1964. [1]
The exception is when neomycin is included, in small quantities, as a preservative in some vaccines – typically 25 μg per dose. [ 6 ] In 2022, the combination of neomycin with dexamethasone and polymyxin B was the 274th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
2 Side effects. 3 Precautions. ... Eye drops can generally be used safely in the ears, ... Polymyxin B, neomycin and hydrocortisone; apply 3-4 drops to the affected ...
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a ...
Colistin Polymyxin B (R=H is polymyxin B2, R=CH 3 is polymyxin B1) Polymyxins are antibiotics. Polymyxins B and E (also known as colistin) are used in the treatment of Gram-negative bacterial infections. They work mostly by breaking up the bacterial cell membrane. They are part of a broader class of molecules called nonribosomal peptides.