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However, only slightly more women than men have Crohn's disease. [250] Parents, siblings or children of people with Crohn's disease are 3 to 20 times more likely to develop the disease. [251] Twin studies find that if one has the disease there is a 55% chance the other will too. [252]
This is most often required due to Crohn's disease in adults and necrotising enterocolitis in young children. [2] Other causes include damage to the small intestine from other means and being born with an abnormally short intestine. [1] It usually does not develop until less than 2 m (6.6 ft) of the normally 6.1 m (20 ft) small intestine remains.
Crohn's disease – also known as regional enteritis, it can occur along any surface of the gastrointestinal tract. The most common location for Crohn's disease to manifest, with or without the involvement of the colon or other parts of the GI tract, is in the terminal ileum (the final segment of the small intestine). [5]
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Jejunoileitis is an uncommon type of Crohn's disease with high morbidity and challenges in medical management. Common symptoms include: Colicky abdominal pain (91%) Weight loss (62%) Diarrhea (53%) Most patients had severe symptoms and required at least one operation for jejunoileitis, with two-thirds of patients requiring two or more operations.
Diseases of the small intestine may present with symptoms such as diarrhoea, malnutrition, fatigue and weight loss. Investigations pursued may include blood tests to monitor nutrition, such as iron levels , folate and calcium , endoscopy and biopsy of the duodenum, and barium swallow .
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